Which drug class inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit and preventing aminoacyl-tRNA attachment?
Correct answer: C. Tetracyclines
- A. Lincosamides
- B. Macrolides
- C. Tetracyclines
- D. Sulfonamides
Explanation
Tetracyclines bind the 30S ribosomal subunit and prevent attachment of aminoacyl-tRNA, thereby inhibiting bacterial protein synthesis. Macrolides and lincosamides mainly bind the 50S subunit, while sulfonamides inhibit folate synthesis.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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