Benzimidazole anthelmintics such as albendazole act mainly by interfering with which parasite structure?
Correct answer: D. Microtubules
- A. Cuticular collagen
- B. Mitochondrial DNA
- C. Neuronal sodium channels
- D. Microtubules
Explanation
Benzimidazoles bind parasite beta-tubulin and disrupt microtubule formation, impairing nutrient uptake and cellular function. Their principal action is therefore different from sodium channel blockers and agents that damage parasite DNA.
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About Veterinary Pharmacology
Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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