Free Renal Physiology MCQs with Answers

39 Renal Physiology MCQs from Physiology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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39 questions · page 1 of 2

  • A. Osmoreceptors in the hypothalamus
  • B. Afferent arterioles of the glomeruli
  • C. Thirst center in the hypothalamus
  • D. Distal tubules and collecting ducts in the kidney

Explanation: ADH acts mainly on V2 receptors in the late distal tubules and collecting ducts, inserting aquaporin-2 channels and increasing water…

Correct answer: Distal tubules and collecting ducts in the kidney
  • A. Adrenaline
  • B. Aldosterone
  • C. A.D.H. and vasopressin
  • D. All of the above

Explanation: Aldosterone increases sodium reabsorption in the distal nephron, with accompanying water retention and increased potassium secretion.

Correct answer: Aldosterone
  • A. Loop of henle
  • B. DCT
  • C. PCT
  • D. Vasa recta

Explanation: About 65% of filtered sodium is reabsorbed in the proximal convoluted tubule through coupled transport with glucose, amino acids…

Correct answer: PCT
  • A. 250
  • B. 800
  • C. 1260
  • D. 1500

Explanation: Renal blood flow is approximately 20–25% of cardiac output, giving a typical value near 1,200–1,300 mL/min in an adult.

Correct answer: 1260
  • A. Na+
  • B. HCO3-
  • C. CL-
  • D. PO4-2

Explanation: In the proximal tubule, NH4⁺ can substitute for H⁺ on the Na⁺/H⁺ exchanger, allowing ammonia-derived acid to be secreted while Na⁺ is…

Correct answer: Na+
  • A. Creatinine clearance
  • B. Renal plasma flow
  • C. G.F.R
  • D. P.A.H. clearance

Explanation: Inulin is freely filtered by the glomerulus and is neither reabsorbed nor secreted by renal tubules, so its clearance equals the…

Correct answer: G.F.R
  • A. Aldosterone
  • B. Angiotensin II
  • C. Vasopressin
  • D. Epinephrine

Explanation: Vasopressin directly increases collecting-duct water permeability, while aldosterone and angiotensin II support sodium and water retention…

Correct answer: Epinephrine
  • A. Inulin and PAH
  • B. Urea and diodrast
  • C. PAH and Phenol red
  • D. Inulin and mannitol

Explanation: Filtration fraction is calculated as GFR divided by renal plasma flow. Inulin clearance estimates GFR and PAH clearance estimates…

Correct answer: Inulin and PAH
  • A. High
  • B. Low
  • C. Same
  • D. Greatly increased

Explanation: Renal glycosuria occurs when glucose appears in urine despite a normal blood glucose level because proximal tubular glucose reabsorption…

Correct answer: Low
  • A. Ammonia
  • B. Potassium
  • C. Bicarbonate
  • D. Sodium

Explanation: The proximal tubule has high permeability to sodium and reabsorbs most of the filtered sodium load, mainly through active transport and…

Correct answer: Sodium
  • A. Proximal segment
  • B. Distal convoluted tubule
  • C. Collecting duct
  • D. Loop of Henle

Explanation: The proximal tubule reabsorbs about 65% of the glomerular filtrate, including large amounts of sodium and water.

Correct answer: Proximal segment
  • A. Plasma oncotic pressure is increased
  • B. Glomerular hydrostatic pressure is decreased
  • C. Tubular hydrostatic pressure is increased
  • D. Increased renal blood flow

Explanation: An increase in renal blood flow can increase glomerular capillary filtration and hence GFR, whereas increased plasma oncotic, tubular…

Correct answer: Increased renal blood flow
  • A. Two million
  • B. One million
  • C. Four million
  • D. ½ million

Explanation: A normal adult kidney contains approximately one million nephrons, although the number varies between individuals.

Correct answer: One million
  • A. 1.5 l/day
  • B. 3 l/day
  • C. 0.5 l/day
  • D. 2 l/day

Explanation: Average adult urine output is about 1 to 2 litres daily, with approximately 1.5 litres per day commonly used as the normal value.

Correct answer: 1.5 l/day
  • A. 100%
  • B. 0%
  • C. 60%
  • D. 50%

Explanation: Under normal conditions, essentially 100% of filtered glucose is reabsorbed in the proximal convoluted tubule through sodium-glucose…

Correct answer: 100%
  • A. More reabsorption in the PCT
  • B. All of these
  • C. More reabsorption of DCT and collecting ducts
  • D. More concentration in loop of Henle

Explanation: Dehydration increases proximal sodium and water reabsorption, strengthens the medullary concentration gradient through the loop of Henle…

Correct answer: All of these
  • A. PAH
  • B. Urea
  • C. Inulin
  • D. Glucose

Explanation: Inulin is freely filtered and neither reabsorbed nor secreted, so the amount cleared from plasma equals the GFR.

Correct answer: Inulin
  • A. Vasopressin
  • B. Erythropoietin
  • C. Renin
  • D. 1,2,5 Dihydroxy cholecalciferol

Explanation: The kidney produces renin, erythropoietin, and active vitamin D, 1,25-dihydroxycholecalciferol.

Correct answer: Vasopressin
  • A. Urea
  • B. Bicarbonate ion
  • C. Chloride
  • D. Carbohydrate

Explanation: Carbonic anhydrase catalyses the reversible reaction between carbon dioxide and water, generating carbonic acid and ultimately bicarbonate…

Correct answer: Bicarbonate ion
  • A. Increase in renal blood flow
  • B. Increase in glomerular filtration rate
  • C. Decrease in reabsorption of Na Cl
  • D. Increase in NaCl concentration in urine

Explanation: In osmotic diuresis, a poorly reabsorbed solute retains water in the tubular fluid and reduces reabsorption of water and accompanying…

Correct answer: Decrease in reabsorption of Na Cl

Renal Physiology MCQs: common questions

Are these Renal Physiology MCQs free?

Yes. All Renal Physiology MCQs from Physiology are free on TestUstad, with unlimited attempts and no account needed. Nothing on this page is a sample or a trial.

How many Renal Physiology MCQs are on this page?

There are 39 Renal Physiology MCQs in the Physiology bank, shown 20 to a page with the correct answer and an explanation on each.

Does every Renal Physiology MCQ have an explanation?

Yes. Each Renal Physiology question shows the correct option and a written explanation of why it is correct, so a wrong answer teaches you something rather than just being marked wrong.

Can I take a timed Renal Physiology test?

Yes. The practice button on this page starts a free Renal Physiology test drawn from the Physiology bank. It marks each answer instantly, gives you a score at the end, and can be retaken as many times as you like.