The primary site of action of antidiuretic hormone is on the_______________?
Correct answer: D. Distal tubules and collecting ducts in the kidney
- A. Osmoreceptors in the hypothalamus
- B. Afferent arterioles of the glomeruli
- C. Thirst center in the hypothalamus
- D. Distal tubules and collecting ducts in the kidney
Explanation
ADH acts mainly on V2 receptors in the late distal tubules and collecting ducts, inserting aquaporin-2 channels and increasing water reabsorption. Its actions on hypothalamic osmoreceptors and the thirst centre regulate secretion and intake rather than being its primary renal site of action.
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