All Free Pharmacology MCQs with Answers

• A. Use in head injury patient
• B. use in impaired pulmonary function
• C. Use of agonist with mixed agonist-antagonist
• D. Use in severe constant pain

Explanation: Severe constant pain is an indication for opioid analgesia, whereas head injury and impaired pulmonary function increase the danger of…

• A. Pulmonary oedema
• B. Emphysema
• C. Bronchial asthma
• D. Head injury

Explanation: Morphine may be used in acute pulmonary oedema because it reduces anxiety and venous return, thereby lowering cardiac preload.

• A. Phenobarbitone
• B. Phenytoin sodium
• C. Primidone
• D. Carbamazepine

Explanation: Carbamazepine is the preferred traditional drug for temporal-lobe, or focal impaired-awareness, epilepsy; phenytoin and phenobarbitone are…

• A. Prochlorperazine
• B. Carbamezapine
• C. Diphenhydramine
• D. Ciprofloxacin

Explanation: Prochlorperazine can produce acute dystonic reactions because of dopamine D2 blockade, causing jaw spasm, trismus, or even mandibular…

• A. Used in trigeminal neuralgia
• B. Carbamazepine is an enzyme inhibitor
• C. Can cause megaloblastic anemia
• D. It is the drug of choice for status epilepticus

Explanation: Carbamazepine is a classic treatment for trigeminal neuralgia and is also useful in focal seizures.

• A. Grand mal epilepsy
• B. Infantile spasm
• C. Petit mal
• D. None of the above

Explanation: Absence, or petit-mal, epilepsy is classically common in school-aged children and presents with brief staring spells.

• A. Carbamazepine
• B. Topiramate
• C. Ethosuxamide
• D. Phenobarbitone

Explanation: Topiramate is an established preventive treatment for migraine and is also an antiepileptic drug.

• A. Head injury
• B. Acute myocardial infarcation
• C. Acute abdominal pain before diagnosis
• D. Bronchial asthma

Explanation: Morphine may be used for severe pain associated with acute myocardial infarction, so this is the exception.

• A. Thiopentone
• B. Ketamine
• C. Propofol
• D. Fentanyl

Explanation: Ketamine produces bronchodilation and is useful for induction in patients at risk of bronchospasm.

• A. Platalets <80,000
• B. Patient on aspirin
• C. Patient on oral anticoagulants
• D. Raised intracranial pressure

Explanation: Aspirin alone usually does not contraindicate spinal or epidural anaesthesia, although bleeding risk must still be assessed.

• A. Propofol
• B. Diazepam
• C. Droperidol
• D. Midazolam

Explanation: Propofol has a rapid onset and very rapid recovery because it is rapidly redistributed and metabolised, with less residual drowsiness than…

• A. Methoxyflurane
• B. Sevoflurane
• C. Desflurane
• D. Isoflurane

Explanation: Sevoflurane is preferred for inhalational induction in children because it is non-irritant and has a relatively rapid onset.

• A. Ketamine
• B. Thiopentone
• C. Tentanyl
• D. Nitrous oxide

Explanation: Ketamine may cause emergence reactions such as vivid dreams, hallucinations and delirium because of its dissociative action.

• A. Cocaine
• B. Etomidate
• C. Cyclopropane
• D. Procaine

Explanation: Cocaine causes marked sympathetic vasoconstriction by blocking norepinephrine reuptake, so it is the exception.

• A. Daroperidol + Fentanyl
• B. Deroperidol + Ketamine
• C. Droperiodl + Ether
• D. Droperiodl + Thiopental sodium + Nitrous oxide

Explanation: Neuroleptanalgesia combines a neuroleptic, droperidol, with a potent opioid analgesic, fentanyl.

• A. Harpes David
• B. Harvey william
• C. Horace wells
• D. Hunter John

Explanation: Horace Wells introduced nitrous oxide for dental analgesia after observing its pain-reducing effects.

• A. Cocaine
• B. Procaine
• C. Lidocaine
• D. Tetracaine

Explanation: Cocaine is a local anaesthetic that also produces powerful central stimulation, including cerebral cortical excitation, by blocking…

• A. Short general anesthetic agent
• B. Local anesthetic agent
• C. Antidepressive agent
• D. Hypnotic agent

Explanation: Ketamine is a short-acting dissociative general anaesthetic that produces analgesia, amnesia and a trance-like state.

• A. Behavioral problem
• B. Sensitizes the heart to adrenaline
• C. Prolonged difficult induction
• D. Tachycardia and or arrhythmias

Explanation: Nitrous oxide may cause excitement, disinhibition and other behavioural changes, especially during induction or recovery.

• A. Thiopental
• B. Halothane
• C. Ethyl Ether
• D. Nitrous oxide

Explanation: Halothane sensitises the myocardium to catecholamines, making ventricular arrhythmias a recognised complication.