All Free Oral Pathology and Medicine MCQs with Answers

• A. Homogenous leukoplakia
• B. Nodular leukoplakia
• C. Verrucous leukoplakia
• D. Ameloblastic fibroma

Explanation: Nodular or speckled leukoplakia contains a greater proportion of epithelial dysplasia and has a higher malignant-transformation risk than…

• A. metastatic breast carcinoma
• B. paget's disease
• C. osteosarcoma
• D. Fibrous dysplasia

Explanation: Asymmetric widening of the periodontal ligament involving multiple adjacent teeth is a classic radiographic warning sign of osteosarcoma.

• A. Ground-glass appearance
• B. Cotton-wool appearance
• C. Soap-bubble appearance
• D. Sun-brust appearance

Explanation: Jaw osteosarcoma may produce a sunburst or sun-ray pattern when malignant osteoid and tumour growth extend through the cortex and…

• A. Irradiation of tissues by implants within the tissues
• B. Irradiation of tissues from a distance of 3 cm
• C. Irradiation of tissues from a distance
• D. Irradiation of tissues by radiopharmaceuticals

Explanation: Brachytherapy is internal radiotherapy, in which radioactive sources are placed within or immediately beside the tumour tissue.

• A. Tongue
• B. Lip
• C. Palate
• D. Floor of the mouth

Explanation: Lip squamous cell carcinoma generally has the best prognosis among the listed oral sites because it is often detected earlier and has more…

• A. Sudden swelling
• B. Paraesthesia
• C. Root resorption
• D. Diffuse radiolucency

Explanation: Paresthesia, especially unexplained numbness in the distribution of the mental or inferior alveolar nerve, is a classic warning sign of…

• A. Ventral surface
• B. Tip of tongue
• C. Posterio 1/3
• D. Lateral margin

Explanation: The lateral border of the tongue is the commonest site for oral tongue carcinoma, particularly the posterolateral region.

• A. Invasion
• B. Degeneration
• C. Pleomorphism
• D. Encpsulation

Explanation: Invasion of malignant epithelial cells through the basement membrane into connective tissue is the decisive histologic evidence of…

• A. Brain
• B. Regional lymph nodes
• C. Lung
• D. Liver

Explanation: Carcinoma of the cheek generally spreads first through lymphatic drainage to the regional cervical and submandibular lymph nodes.

• A. chronic hypertrophic candidiasis
• B. Dental ulcers
• C. Leukoplakia
• D. atrophic glossitis

Explanation: Leukoplakia is the most common clinically recognised potentially malignant oral lesion and may show dysplasia or evolve into squamous cell…

• A. occurs mostly is female
• B. metastases easily
• C. is mostly basal cell type
• D. occurs mostly in the lower lip

Explanation: Most lip carcinomas arise on the sun-exposed lower lip, where chronic ultraviolet exposure is important.

• A. Burkitts lymphoma
• B. Cherubism
• C. Garrey's osteomyelitis
• D. Pagets disease

Explanation: Burkitt lymphoma produces a starry-sky pattern because pale tingible-body macrophages are scattered among densely packed tumour cells.

• A. Squamous cell carcinoma
• B. Verrucous carcinoma
• C. Kaposi sarcoma
• D. Multiple myeloma

Explanation: Kaposi sarcoma is the most commonly reported oral malignancy associated with HIV infection, often appearing as red, purple, or brown…

• A. Apex
• B. Base
• C. Dorsum
• D. Lateral borders

Explanation: The lateral or posterolateral border of the tongue is the commonest site for oral squamous cell carcinoma because it is exposed to chronic…

• A. Malar region
• B. Lower lip
• C. Forehead
• D. Upper lip

Explanation: On the orofacial skin, melanoma is classically associated with the malar or cheek region.

• A. Syphilitic glossitis and Mikulicz's syndrome
• B. Syphilitic glossitis and plummer vinson syndrome
• C. Plummer vinson disease and hepatitis A
• D. Hepatitis A and Mikulicz's Syndrome

Explanation: Syphilitic glossitis and Plummer-Vinson syndrome are recognized risk conditions for squamous cell carcinoma, particularly involving the…

• A. Tell patient no malignancy
• B. Observe the patient for twelve months
• C. Repeat the biopsy
• D. Observe the patient for three months

Explanation: A negative biopsy does not exclude malignancy when the clinical appearance remains suspicious, because sampling error is possible.

• A. Alport syndrome
• B. Ehlers-Danlos syndrome
• C. Marfan syndrome
• D. McArdle's disease

Explanation: McArdle disease is a glycogen storage disorder caused by muscle phosphorylase deficiency, not a connective-tissue disorder.

• A. Autosomal dominant inheritance
• B. Inability to repair sunlight induced damage to DNA
• C. Irregular accemulation of melanin in the basal cell layer
• D. Acanthosis of epithelium with elongation of rete ridges

Explanation: Xeroderma pigmentosum results from defective nucleotide-excision repair, so ultraviolet-induced DNA damage accumulates and greatly…

• A. Lichen planus
• B. sarcoidosis
• C. pyostomatitis vegentanus
• D. Dermatitis herpetiformis

Explanation: Pyostomatitis vegetans is a characteristic oral manifestation of inflammatory bowel disease, especially ulcerative colitis.