Free Immunology MCQs with Answers

90 Immunology MCQs from Microbiology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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90 questions · page 5 of 5

  • A. Delayed reaction
  • B. Immediate reaction
  • C. passive transfer by serum
  • D. None of the above

Explanation: Anaphylaxis is an immediate type I hypersensitivity reaction that can be passively transferred by serum containing IgE.

Correct answer: Delayed reaction
  • A. IgG
  • B. IgD
  • C. IgM
  • D. IgA

Explanation: IgA is the principal immunoglobulin in exocrine secretions such as saliva, tears, intestinal fluid and breast milk, where secretory IgA…

Correct answer: IgA
  • A. Lysosomes
  • B. Proteolytic enzymes
  • C. Lymphotoxins
  • D. Vasoactive mediators

Explanation: Mast-cell granules contain vasoactive mediators such as histamine, which cause vasodilation, increased vascular permeability and…

Correct answer: Vasoactive mediators
  • A. Atopic allergy
  • B. Serum sickness
  • C. Transfusion reaction
  • D. Contact dermatitis

Explanation: Serum sickness is a classic type III hypersensitivity reaction caused by deposition of circulating antigen-antibody immune complexes.

Correct answer: Serum sickness
  • A. C2a
  • B. C3b
  • C. C4a
  • D. C5a

Explanation: C5a is the strongest chemotactic complement fragment and attracts neutrophils and other leukocytes to sites of inflammation.

Correct answer: C5a
  • A. IgA
  • B. IgD
  • C. IgE
  • D. IgG

Explanation: Secretory IgA is the predominant immunoglobulin in saliva and other mucosal secretions, where it prevents microbial attachment and…

Correct answer: IgA
  • A. Salk vaccine
  • B. Tetanus toxoid
  • C. Sabin's oral vaccine
  • D. All of the above

Explanation: The Salk polio vaccine contains inactivated poliovirus. Sabin vaccine uses live attenuated virus, while tetanus toxoid contains…

Correct answer: Salk vaccine
  • A. Synovial fluid
  • B. Myocardium
  • C. Cardiac valves
  • D. Vascular intima

Explanation: The group A streptococcal carbohydrate contains N-acetylglucosamine, which can cross-react with components of cardiac valves in rheumatic…

Correct answer: Cardiac valves
  • A. CD 4*
  • B. CD 8*
  • C. B - lymphocytes
  • D. None of the above

Explanation: Protection against tuberculosis is mainly cell-mediated and is initiated by CD4 helper T cells, especially Th1 cells, which activate…

Correct answer: CD 4*
  • A. Hemoral immunity
  • B. Cell mediated immunity
  • C. Complement function
  • D. Phagocyte dysfunction

Explanation: The tuberculin skin test is a delayed-type hypersensitivity reaction mediated by sensitised T lymphocytes, so it reflects cell-mediated…

Correct answer: Cell mediated immunity