Moderate

Group A carbohydrate of Str. pyogenes cross reacts with human_________________?

Correct answer: C. Cardiac valves

  • A. Synovial fluid
  • B. Myocardium
  • C. Cardiac valves
  • D. Vascular intima

Explanation

The group A streptococcal carbohydrate contains N-acetylglucosamine, which can cross-react with components of cardiac valves in rheumatic heart disease. Myocardial cross-reactivity is more classically associated with antibodies against streptococcal M protein.

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