The interaction of antigens with antibodies on the surface of a mast cel leads to degranulation and anaphylaxis. The mast cell granules produce anaphylaxis because they contain________________?

Correct answer: D. Vasoactive mediators

  • A. Lysosomes
  • B. Proteolytic enzymes
  • C. Lymphotoxins
  • D. Vasoactive mediators

Explanation

Mast-cell granules contain vasoactive mediators such as histamine, which cause vasodilation, increased vascular permeability and bronchoconstriction during anaphylaxis. Proteolytic enzymes may also be present, but they are not the main mediators responsible for the anaphylactic effects.

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