Free Circulation MCQs with Answers

695 Circulation MCQs from Biology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

The circulatory system covers the chambers, valves and conducting pathway of the human heart, along with the cardiac cycle and control of heartbeat. It compares arteries, veins and capillaries by structure and function, and explains how the lymphatic system returns tissue fluid, transports absorbed fats and supports immunity.

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695 questions · page 3 of 35

Moderate
  • A. atherosclerosis
  • B. arthritis
  • C. anaemia
  • D. haemophilia

Explanation: Plaques of cholesterol and debris narrow and stiffen arteries, raising blood pressure and predisposing to clots that cause heart attacks…

Correct answer: atherosclerosis
Moderate
  • A. tonsils
  • B. spleen
  • C. thymus
  • D. lymph node

Explanation: The spleen sits in the abdomen and acts on blood the way lymph nodes act on lymph, trapping pathogens and recycling old erythrocytes.

Correct answer: spleen
Moderate
  • A. along the spinal cord
  • B. in the thorax around the heart
  • C. in the throat, guarding the entrances of the respiratory and digestive tracts
  • D. inside the bone marrow

Explanation: Their position at the back of the mouth and nose lets them sample inhaled and swallowed material and mount early immune responses.

Correct answer: in the throat, guarding the entrances of the respiratory and digestive tracts
  • A. capillaries of the tissues
  • B. aorta
  • C. pulmonary vein
  • D. subclavian veins near the neck

Explanation: The thoracic duct and right lymphatic duct empty lymph into the subclavian veins, restoring fluid and proteins that leaked from the…

Correct answer: subclavian veins near the neck
Moderate
  • A. T lymphocytes mature
  • B. red blood cells are produced
  • C. antibodies are stored
  • D. platelets are formed

Explanation: Immature lymphocytes from the bone marrow migrate to the thymus, where they learn to distinguish self from non self.

Correct answer: T lymphocytes mature
  • A. contains more red blood cells than blood
  • B. has no red blood cells and less protein
  • C. flows away from the heart through arteries
  • D. contains no white blood cells

Explanation: Lymph is essentially filtered tissue fluid, so it lacks erythrocytes and is poorer in plasma proteins, though it carries lymphocytes.

Correct answer: has no red blood cells and less protein
Hard
  • A. they fill with excess tissue fluid
  • B. bacteria dissolve inside them
  • C. lymphocytes multiply rapidly inside them to fight the pathogen
  • D. their valves close and trap lymph

Explanation: Trapped antigens trigger lymphocyte proliferation within the node, enlarging it and making it tender.

Correct answer: lymphocytes multiply rapidly inside them to fight the pathogen
Hard
  • A. thick muscular walls like arteries
  • B. red blood cells
  • C. pacemakers
  • D. valves that keep the lymph moving in one direction

Explanation: Lymph flows under very low pressure, so valves prevent backflow while surrounding muscle contractions squeeze it onwards.

Correct answer: valves that keep the lymph moving in one direction
Easy
  • A. Lungs
  • B. Body
  • C. Right atrium
  • D. Pulmonary artery

Explanation: The left ventricle pumps oxygenated blood through the aorta to the entire body (systemic circulation).

Correct answer: Body
Easy
  • A. AV bundle
  • B. Pacemaker of the heart
  • C. Valve of the heart
  • D. Coronary artery

Explanation: The sinoatrial (SA) node in the right atrium is the natural pacemaker, initiating each heartbeat.

Correct answer: Pacemaker of the heart
Fairly easy
  • A. Vena cava
  • B. Pulmonary vein
  • C. Aorta
  • D. Capillary

Explanation: The aorta has the thickest wall to withstand the high pressure of blood ejected from the left ventricle.

Correct answer: Aorta
Fairly easy
  • A. Vitamin A
  • B. Vitamin K
  • C. Vitamin C
  • D. Vitamin D

Explanation: Vitamin K is required for synthesis of clotting factors II, VII, IX, and X in the liver.

Correct answer: Vitamin K
Hard
  • A. Atrial depolarization
  • B. Ventricular depolarization
  • C. Atrial repolarization
  • D. Ventricular repolarization

Explanation: The QRS complex represents ventricular depolarization (contraction); the P wave is atrial depolarization.

Correct answer: Ventricular depolarization
Fairly easy
  • A. Lymphocytes
  • B. Monocytes
  • C. Neutrophils
  • D. Eosinophils

Explanation: Neutrophils are the most abundant WBCs (60-70%), functioning as primary phagocytes against bacteria.

Correct answer: Neutrophils
Hard
  • A. Active transport
  • B. Ultrafiltration from capillaries
  • C. Secretion by cells
  • D. Osmosis only

Explanation: Tissue fluid forms by ultrafiltration from arterial ends of capillaries due to hydrostatic pressure.

Correct answer: Ultrafiltration from capillaries
Moderate
  • A. Heart rate + Stroke volume
  • B. Heart rate × Stroke volume
  • C. Heart rate - Stroke volume
  • D. Stroke volume only

Explanation: Cardiac output (mL/min) = Heart rate (beats/min) × Stroke volume (mL/beat).

Correct answer: Heart rate × Stroke volume
Moderate
  • A. Return tissue fluid to blood
  • B. Fat absorption
  • C. Immune defense
  • D. Oxygen transport

Explanation: Oxygen transport is a function of blood, not lymph. Lymph returns tissue fluid, absorbs fats, and contains immune cells.

Correct answer: Oxygen transport
Hard
  • A. Prothrombin
  • B. Thrombin
  • C. Calcium
  • D. Platelets

Explanation: Thrombin converts soluble fibrinogen to insoluble fibrin, forming the mesh of blood clots.

Correct answer: Thrombin
  • A. Deficiency of oxygen
  • B. Loss of nerve signals
  • C. Drop in blood pressure
  • D. Excess fluid accumulation in tissue

Explanation: The lymphatic system is the only route by which surplus tissue fluid returns to the blood, so blocking it lets fluid collect between the…

Correct answer: Excess fluid accumulation in tissue
  • A. Arteries: Due to thick walls
  • B. Capillaries: due to highest overall cross-sectional area
  • C. Veins: due to blood flow against the gravity
  • D. Capillaries: Due to two-way blood flow in capillaries

Explanation: Although each capillary is tiny, there are so many in parallel that their combined cross sectional area is far greater than that of the…

Correct answer: Capillaries: due to highest overall cross-sectional area