The first consequence of lymphatic blockage in tissues is:
Correct answer: D. Excess fluid accumulation in tissue
- A. Deficiency of oxygen
- B. Loss of nerve signals
- C. Drop in blood pressure
- D. Excess fluid accumulation in tissue
Explanation
The lymphatic system is the only route by which surplus tissue fluid returns to the blood, so blocking it lets fluid collect between the cells and the limb swells, which is the oedema of filariasis. Blood flow through the arteries and capillaries continues normally, so oxygen delivery and blood pressure are not affected first. The swelling is soft and painless in the early stages for exactly this reason.
This question appeared on the UHS MDCAT 2025 paper, which you can sit online with every answer explained.
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About Lymphatic System
The lymphatic system returns excess tissue fluid to the bloodstream and supports immune defence through lymph, lymph vessels, lymph nodes, the spleen, thymus and tonsils. It also transports absorbed fats from intestinal lacteals, which distinguishes lymphatic circulation from the blood vascular system.
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