Free Lipids MCQs with Answers

• A. Amino acids
• B. Fatty acids
• C. None of the above
• D. Cholesterol

Explanation: Cholesterol is the parent precursor from which steroid hormones, bile acids and vitamin D are synthesized.

• A. HDL
• B. VLDL
• C. LDL
• D. Chylomicrons

Explanation: HDL carries cholesterol from peripheral tissues back to the liver for disposal or recycling, a process called reverse cholesterol…

• A. Lipo oxygenase inhibition
• B. Cyclo-oxygenase inhibition
• C. Reductase
• D. Peroxidase

Explanation: Cyclo-oxygenase converts arachidonic acid into prostaglandin precursors, so inhibiting this enzyme reduces prostaglandin synthesis.

• A. Growth hormone
• B. Cortisol
• C. Insulin
• D. Gulcagon

Explanation: Insulin promotes triglyceride synthesis by increasing glucose entry, acetyl-CoA formation and fatty-acid synthesis, while also favouring…

• A. Egg yolk
• B. Coconut oil
• C. Hydrogenated fat
• D. Ghee (unsaturated)

Explanation: Egg yolk contains a substantial amount of cholesterol because it is part of the animal cell membrane and developing embryo supply.

• A. Increasing acetyl-CoA corboxylase activity
• B. Inhibits Pyruvate dehydrogenase
• C. Increases the transport of glucose in to the cells
• D. Decreases intracellular cAMP level

Explanation: Insulin stimulates, rather than inhibits, pyruvate dehydrogenase, increasing acetyl-CoA supply for fatty-acid synthesis.

• A. Mitochondria
• B. Nucleus
• C. Cytosol
• D. None of the above

Explanation: De novo fatty-acid synthesis occurs mainly in the cytosol, where acetyl-CoA is converted to malonyl-CoA and then elongated by fatty-acid…

• A. All of the above
• B. Resting state
• C. Active state
• D. Fasting state

Explanation: During fasting, low insulin and increased counter-regulatory hormones activate hormone-sensitive lipase in adipose tissue, releasing free…

• A. Transport cholesterol from liver to peripheral tissues
• B. None of the above
• C. Both of the above
• D. Esterification with PUFA

Explanation: HDL mainly carries cholesterol from peripheral tissues back to the liver in reverse cholesterol transport.

• A. Glycolysis
• B. Kreb's cycle
• C. Pentose phosphate pathway
• D. Urea cycle

Explanation: Fatty acid synthesis requires NADPH as its reducing equivalent, supplied mainly by the pentose phosphate pathway.

• A. has a high caloric value
• B. is necessary for storage of carbohydrates
• C. aids in absorption of carbohydrates
• D. Provides essential fatty acid

Explanation: Dietary lipid is required particularly because it supplies essential fatty acids, which humans cannot synthesize and must obtain from…

• A. Glucose
• B. Cholesterol
• C. Ketone bodies
• D. Fat

Explanation: Even-chain fatty acids yield acetyl-CoA, which can form ketone bodies, cholesterol, and fat but cannot produce net glucose.

• A. VLDL
• B. HDL
• C. Chylomicrons
• D. LDL

Explanation: Chylomicrons contain the highest proportion of triacylglycerol because they transport dietary fat from the intestine.

• A. Succinyl CoA
• B. Malonyl CoA
• C. Acetyl CoA
• D. Propionyl CoA

Explanation: Odd-chain fatty acid beta-oxidation ends with a three-carbon propionyl-CoA residue, unlike even-chain fatty acids, which end entirely as…

• A. Short acting
• B. Present in many tissues
• C. Some require C-AMP for their action
• D. All are true

Explanation: Prostaglandins are locally acting, short-lived compounds found in many tissues, and some exert their effects through cyclic AMP.

• A. VLDL
• B. LDL
• C. Chylomicrons
• D. HDL

Explanation: Endogenous triacylglycerol is synthesized mainly in the liver and transported through plasma in VLDL.

• A. Clofibrate
• B. Gemfibrosil
• C. Lovastatin
• D. cholestyramine

Explanation: Lovastatin competitively inhibits HMG-CoA reductase, the rate-limiting enzyme of cholesterol synthesis.

• A. Cholesterol
• B. Leucine
• C. Ketone bodies
• D. Bile acids

Explanation: HMG-CoA is an intermediate in cholesterol synthesis and ketogenesis, and it can also arise during leucine catabolism.

• A. Acetyl CoA
• B. Acetic acid
• C. Oxalo acetic acid
• D. PyruvateFind Chemistry Tutors

Explanation: Acetyl-CoA is the two-carbon starting material for cholesterol synthesis; it condenses to form acetoacetyl-CoA and then HMG-CoA.

• A. Chenodeoxy cholic acid
• B. Cholecystokinin
• C. Testosterone
• D. Glycocholic acid

Explanation: Chenodeoxycholic acid, glycocholic acid and testosterone are synthesized from cholesterol.