HMG CoA reductase is inhibited by_____________?
Correct answer: C. Lovastatin
- A. Clofibrate
- B. Gemfibrosil
- C. Lovastatin
- D. cholestyramine
Explanation
Lovastatin competitively inhibits HMG-CoA reductase, the rate-limiting enzyme of cholesterol synthesis. Clofibrate and gemfibrozil mainly activate fatty-acid oxidation, while cholestyramine binds bile acids in the intestine.
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