Free Clinical Biochemistry MCQs with Answers

39 Clinical Biochemistry MCQs from Biochemistry, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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  • A. 80 mg%
  • B. 100 mg%
  • C. 180 mg/ dl
  • D. 200 mg%

Explanation: The renal threshold for glucose is about 180 mg/dL, above which the renal tubules cannot reabsorb all filtered glucose and glucosuria may…

Correct answer: 180 mg/ dl
  • A. Urea
  • B. Creatine
  • C. glucose
  • D. None of the aboveFind Chemistry Tutors

Explanation: Glucose is normally almost completely reabsorbed by the renal tubules and is absent from urine, except when blood glucose exceeds the…

Correct answer: glucose
  • A. Glucose 1 phosphatase
  • B. Glucose 1,6 phosphatase
  • C. Glucose 6 phosphatase
  • D. Myophosphorylase

Explanation: McArdle disease is caused by deficiency of muscle glycogen phosphorylase, also called myophosphorylase.

Correct answer: Myophosphorylase
  • A. Cytochrome P-450
  • B. Glutathione S-transferase
  • C. NADPH cytochrome P-450 reductase
  • D. Glucuronyl transferase

Explanation: Cytochrome P-450 carries out the major Phase I oxidation reactions that activate or modify many xenobiotics.

Correct answer: Cytochrome P-450
  • A. Gaucher's disease
  • B. Zellweger's syndrome
  • C. Epidermolysis bullosa
  • D. Leber's neuropathy

Explanation: Zellweger syndrome results from defective peroxisome formation or function, causing accumulation of very-long-chain fatty acids and…

Correct answer: Zellweger's syndrome
  • A. Alkaline phosphatase
  • B. SGOT
  • C. CPK
  • D. SGPT

Explanation: Creatine phosphokinase, now called creatine kinase, is abundant in skeletal muscle and is released after muscle injury.

Correct answer: CPK
  • A. CPK
  • B. LDH
  • C. SGOT
  • D. Amylase

Explanation: Creatine phosphokinase, now called creatine kinase, is among the earliest listed enzymes to rise after myocardial infarction, usually…

Correct answer: CPK
  • A. MM fraction
  • B. MB fraction
  • C. BB fraction
  • D. Both MM and BB fraction

Explanation: CK-MB is the creatine kinase isoenzyme relatively concentrated in cardiac muscle, so it rises after myocardial infarction.

Correct answer: MB fraction
  • A. Glutamate oxaloacetate transaminase
  • B. Glutamate pyruvate transaminase
  • C. Alkaline phosphaase
  • D. Acid phosphatase

Explanation: Alkaline phosphatase is markedly increased in cholestasis and obstructive jaundice because bile obstruction enhances its release from the…

Correct answer: Alkaline phosphaase
  • A. Deficiency of glutamic acid
  • B. Deficiency of oxaloacetic acid
  • C. All of the above
  • D. Liver disease

Explanation: SGOT, now called AST, rises in liver injury, although it is not liver-specific and can also increase in cardiac or skeletal muscle damage.

Correct answer: Liver disease
  • A. Haemoglobin
  • B. A & B
  • C. Gall bladder
  • D. Myoglobin

Explanation: Bilirubin is formed when heme from haemoglobin and other haemoproteins, including myoglobin, is degraded.

Correct answer: A & B
  • A. All of the above
  • B. Chenodeoxycholic acid
  • C. Deoxycholic acid
  • D. Lithocholic acid
  • E. Cholic acid

Explanation: Bile contains primary bile acids such as cholic and chenodeoxycholic acids, along with secondary bile acids such as deoxycholic and…

Correct answer: All of the above
  • A. Serotonin
  • B. Thyroxine
  • C. Triidothyronine
  • D. Parathyroid hormone

Explanation: Calcitonin lowers blood calcium mainly by inhibiting osteoclast-mediated bone resorption, opposing the calcium-raising action of…

Correct answer: Parathyroid hormone
  • A. 1 : 1
  • B. 30 : 1
  • C. 15 : 1
  • D. 20 : 1

Explanation: The bicarbonate buffer equation is pH = 6.1 + log([HCO3−]/[H2CO3]); at pH 7.4, the ratio is 10^1.3, approximately 20:1.

Correct answer: 20 : 1
  • A. Hydrolase
  • B. Oxidase
  • C. Peroxidase
  • D. Dehydrogenase

Explanation: The respiratory burst begins when NADPH oxidase is activated in phagocytes, producing superoxide from molecular oxygen.

Correct answer: Oxidase
  • A. 3 - 4 mg%
  • B. 1 - 3 mg%
  • C. 0.5 - 1 mg%
  • D. 4 - 5.5 mg%

Explanation: Normal total blood bilirubin is approximately 0.2–1.2 mg/dL, commonly rounded in exam texts to about 0.5–1 mg%.

Correct answer: 0.5 - 1 mg%
  • A. Proteins
  • B. K+
  • C. Cl
  • D. Na+

Explanation: Sodium is the principal extracellular cation and therefore the main electrolyte in ECF.

Correct answer: Na+
  • A. Any of the above
  • B. Reduction
  • C. Conjugation
  • D. Oxidation

Explanation: Detoxification reactions include oxidation, reduction and conjugation. Oxidation or reduction modifies a compound, while conjugation…

Correct answer: Any of the above
  • A. Cytochrome
  • B. Cytochrome C
  • C. Cytochrome P450
  • D. Cytochrome A

Explanation: Cytochrome P450 is a family of microsomal enzymes that carries out many drug oxidation and other phase I biotransformation reactions.

Correct answer: Cytochrome P450
  • A. 100-140 mgs/100 ml
  • B. 260-360 mgs/100 ml
  • C. 80-250 mgs/100 ml
  • D. 150-250 mgs/100 ml

Explanation: A traditional reference range for total serum cholesterol is approximately 150–250 mg/dL, making that the closest listed range.

Correct answer: 150-250 mgs/100 ml

Clinical Biochemistry MCQs: common questions

Are these Clinical Biochemistry MCQs free?

Yes. All Clinical Biochemistry MCQs from Biochemistry are free on TestUstad, with unlimited attempts and no account needed. Nothing on this page is a sample or a trial.

How many Clinical Biochemistry MCQs are on this page?

There are 39 Clinical Biochemistry MCQs in the Biochemistry bank, shown 20 to a page with the correct answer and an explanation on each.

Does every Clinical Biochemistry MCQ have an explanation?

Yes. Each Clinical Biochemistry question shows the correct option and a written explanation of why it is correct, so a wrong answer teaches you something rather than just being marked wrong.

Can I take a timed Clinical Biochemistry test?

Yes. The practice button on this page starts a free Clinical Biochemistry test drawn from the Biochemistry bank. It marks each answer instantly, gives you a score at the end, and can be retaken as many times as you like.