McArdles disease is due to the deficiency of_____________?
Correct answer: D. Myophosphorylase
- A. Glucose 1 phosphatase
- B. Glucose 1,6 phosphatase
- C. Glucose 6 phosphatase
- D. Myophosphorylase
Explanation
McArdle disease is caused by deficiency of muscle glycogen phosphorylase, also called myophosphorylase. This blocks glycogen breakdown in skeletal muscle and causes exercise-induced cramps and myoglobinuria.
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