Which stain commonly demonstrates the metachromatic granules of mast cells in tissue sections?
Correct answer: D. Toluidine blue
- A. Masson's trichrome
- B. Oil Red O
- C. Prussian blue
- D. Toluidine blue
Explanation
Toluidine blue stains mast cell granules metachromatically because of their sulfated glycosaminoglycans. Oil Red O detects neutral lipid, Prussian blue detects iron, and Masson's trichrome highlights connective tissue.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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