In canine parvoviral enteritis, the principal intestinal cells damaged by viral replication are found in the:
Correct answer: B. Crypt epithelium
- A. Tips of mature villi
- B. Crypt epithelium
- C. Muscularis externa
- D. Serosal connective tissue
Explanation
Canine parvovirus targets rapidly dividing crypt epithelial cells, causing crypt necrosis and subsequent villous collapse. Mature villus tip cells are affected secondarily as damaged crypts fail to replace them.
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Covers the causes and mechanisms of disease, cellular injury, inflammation, healing, circulatory disturbances, neoplasia and disorders of major organs. It also includes gross and microscopic pathological changes, specimen interpretation and the distinction between aetiology, pathogenesis, clinical signs and lesions.
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