Which one of the following does not apply to RNA?
Correct answer: B. Chargaff's rule
- A. Heterocyclic nitrogenous bases
- B. Chargaff's rule
- C. Complementary base pairing
- D. 5' phosphoryl and 3' hydroxyl ends
Explanation
Chargaff's rules apply only to double-stranded DNA molecules. These do not apply to single-stranded DNA or RNA molecules. Chargaff's rules state that DNA helices contain equal molar ratios of A and T, G and C. This is because in a DNA molecule, complementary base pairing occurs between A and T, and C and G base pairs. This complementary base pairing is not possible in the case of a single-stranded RNA molecule. Thus, Chargaff's rules do not apply to RNA.
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