The association of histone H1 with a nucleosome indicates that:
Correct answer: B. The DNA is condensed into a chromatin fibre
- A. DNA replication is occurring
- B. The DNA is condensed into a chromatin fibre
- C. The DNA double helix is exposed
- D. Transcription is occurring
Explanation
Histones help in the packaging of DNA. In eukaryotes, DNA packaging is carried out with the help of positively charged basic proteins called histones. Histones are of five types - H-1, H-2A, H-2B, H-3, and H-4. H1 is attached to the linker DNA. Histone contains a large proportion of the positively charged (basic) amino acids, lysine, and arginine in its structure. DNA is negatively charged due to the phosphate groups on its backbone. The result of these opposite charges is a strong attraction and, therefore, a high binding affinity between histones and DNA.
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About Chromosomes
Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.
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