Which of the following derivatives cannot be prepared directly from carboxylic acid?
Correct answer: B. Acid amide
- A. Acid halide
- B. Acid amide
- C. Ester
- D. Acid anhydride
Explanation
The direct reaction of a carboxylic acid with ammonia results in an acid-base reaction, forming an ammonium carboxylate salt. This salt must then be heated to dehydrate it to form the acid amide. The other derivatives can be formed in a single step.
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About Carboxylic Acid Derivatives
Carboxylic acid derivatives include acid halides, acid anhydrides, esters and amides, formed by replacing the hydroxyl group of a carboxylic acid. Their nomenclature, structures, preparation, hydrolysis and relative reactivity are linked through nucleophilic acyl substitution, which differs from the nucleophilic addition reactions of aldehydes and ketones.
Practise Carboxylic Acids
550 free Carboxylic Acids MCQs from Chemistry, each with the correct answer and an explanation. Unlimited attempts, no account needed.
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