Which mechanism explains how trimethoprim inhibits bacterial growth?
Correct answer: A. It blocks bacterial folic acid synthesis
- A. It blocks bacterial folic acid synthesis
- B. It disrupts fungal ergosterol production
- C. It prevents viral protein attachment
- D. It inhibits parasite muscle contraction
Explanation
Trimethoprim inhibits bacterial dihydrofolate reductase, reducing folic acid needed for nucleic acid production. The other options describe antifungal, antiviral or antiparasitic mechanisms rather than trimethoprim action.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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