Before administering primaquine for a malaria infection, which assessment is especially important?
Correct answer: B. Whether the patient has glucose-6-phosphate dehydrogenase deficiency
- A. Whether the patient has a history of motion sickness
- B. Whether the patient has glucose-6-phosphate dehydrogenase deficiency
- C. Whether the patient received a tetanus booster this year
- D. Whether the patient has previously used an antifungal cream
Explanation
Primaquine can cause severe haemolysis in patients with glucose-6-phosphate dehydrogenase deficiency, so screening or confirmation of G6PD status is important before treatment. The other assessments do not identify this specific serious risk.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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