Which laboratory result is most important to monitor in a patient receiving prolonged ketoconazole therapy?
Correct answer: A. Serum liver transaminase levels
- A. Serum liver transaminase levels
- B. Serum calcium concentration
- C. Haemoglobin A1c level
- D. Peak expiratory flow rate
Explanation
Systemic ketoconazole can cause serious hepatotoxicity, so liver function requires monitoring. The other tests do not directly identify the major predictable toxicity of this antifungal drug.
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About Antimicrobial Drugs
Antimicrobial pharmacology covers antibiotics, antitubercular, antifungal, antiviral and antiparasitic drugs, including their targets, clinical uses, resistance and major adverse effects. Questions distinguish bactericidal from bacteriostatic action, narrow from broad spectrum therapy, and antimicrobial treatment from supportive management of infection.
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