Which drug class is most appropriate for reducing gastric acid secretion by blocking the proton pump in parietal cells?
Correct answer: A. Proton pump inhibitors
- A. Proton pump inhibitors
- B. Muscarinic agonists
- C. Loop diuretics
- D. Cholinesterase inhibitors
Explanation
Proton pump inhibitors such as omeprazole block the gastric hydrogen-potassium ATPase, the final step in acid secretion. The other classes do not selectively inhibit this parietal cell proton pump.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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