What is the main pharmacological action of glucocorticoids in inflammatory disease?
Correct answer: B. Suppression of inflammatory mediator production
- A. Direct stimulation of bacterial growth
- B. Suppression of inflammatory mediator production
- C. Inhibition of renal sodium excretion only
- D. Activation of skeletal muscle contraction
Explanation
Glucocorticoids suppress inflammation by altering gene transcription and reducing the production of cytokines, prostaglandins and other mediators. Their effects are broader than simple inhibition of renal sodium handling.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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