Thiamine deficiency causes decreased energy production because____________?
Correct answer: D. It is co-enzyme for pyruvate dehydrogenase
- A. It is required for the process of transmination
- B. It is co-factor in oxidative reduction
- C. It is co-enzyme for transketolase in pentose phosphate pathway
- D. It is co-enzyme for pyruvate dehydrogenase
Explanation
Thiamine pyrophosphate is a coenzyme for pyruvate dehydrogenase, allowing pyruvate to enter acetyl-CoA formation and the TCA cycle for energy production. It also supports transketolase, but that pathway is not the main explanation for reduced cellular energy in this context.
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