Free Metabolism and Bioenergetics MCQs with Answers
68 Metabolism and Bioenergetics MCQs from Biochemistry, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.
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- A. Glucose synthesis
- B. Glycogen synthesis
- C. Protein syntehsis
- D. Fatty acid synthesis
Explanation: Insulin promotes storage and synthesis by increasing fatty-acid, glycogen, and protein synthesis.
Correct answer: Glucose synthesis- A. Glucose 1,6 diphosphate dehydrogenase
- B. Glucose 1 phosphate dehydrogenase
- C. Glucose 6 phosphate dehydrogenase
- D. All of the above
Explanation: Glucose-6-phosphate dehydrogenase catalyses the first step of the pentose phosphate pathway and produces NADPH.
Correct answer: Glucose 6 phosphate dehydrogenase- A. ATP
- B. ADP
- C. Acetyl CoA
- D. NADPH
Explanation: The HMP shunt, or pentose phosphate pathway, produces NADPH for reductive biosynthesis and antioxidant protection, along with…
Correct answer: NADPH- A. Transketolase
- B. 6 phosphogluconate dehydrogenase
- C. G6 PD
- D. Transaldolase
Explanation: Transketolase transfers a two-carbon unit in the HMP shunt and requires thiamine pyrophosphate, the active coenzyme form of vitamin B1.
Correct answer: Transketolase- A. Glycogenolysis and Gluconeogenesis
- B. Glycolysis and citric acid cycle
- C. Embden-Meyerhof Pathway and H.M.P shunt
- D. Glycogenolysis and Citric and cycleOrder DNA Kits
Explanation: The brain primarily obtains energy by oxidising glucose through glycolysis, followed by the citric acid cycle and oxidative…
Correct answer: Glycolysis and citric acid cycle- A. Muscle
- B. All of the above
- C. Heart
- D. RBC
Explanation: Mature red blood cells lack mitochondria, so they cannot carry out the mitochondrial TCA cycle and depend on glycolysis for ATP.
Correct answer: RBC- A. Citrate
- B. Isocitrate
- C. Succinate
- D. Fumarate
Explanation: Citrate is the first compound formed when acetyl-CoA condenses with oxaloacetate in the TCA cycle.
Correct answer: Citrate- A. Alpha ketoglutrate to succinyl CoA
- B. Succinyl CoA to Succinate
- C. Succinate to fumarate
- D. Oxalocetate to citrate
Explanation: Substrate-level phosphorylation in the TCA cycle occurs when succinyl-CoA is converted to succinate, producing GTP or ATP directly.
Correct answer: Succinyl CoA to Succinate- A. Nucleus
- B. Ribosomes
- C. Mitochondria
- D. Nonparticulate cytoplasm
Explanation: In eukaryotic cells, most citric acid cycle enzymes are located in the mitochondrial matrix, while succinate dehydrogenase is embedded in…
Correct answer: Mitochondria- A. Oleic acid
- B. Alanine
- C. Glycerol
- D. Tryptophan
Explanation: Oleic acid is an even-chain fatty acid whose acetyl-CoA products cannot give a net synthesis of glucose in humans.
Correct answer: Oleic acid- A. 2- phospho glyceric acid
- B. Dihydroxy acetone phosphate
- C. 3- phospho glyceralehyde
- D. 3- phospho glyceric acid
Explanation: Glycerol is converted to glycerol 3-phosphate and then oxidised to dihydroxyacetone phosphate, which is a glycolytic intermediate.
Correct answer: Dihydroxy acetone phosphate- A. Amino acids
- B. Glycerol
- C. Acetoacetate
- D. Lactic acid
Explanation: Amino acids, glycerol and lactate can enter gluconeogenic pathways and form glucose.
Correct answer: Acetoacetate- A. Alanine
- B. Glycerol
- C. Ketones
- D. Lactate
Explanation: Lactate makes a major contribution to gluconeogenesis through the Cori cycle: the liver converts lactate from exercising muscle and red…
Correct answer: Lactate- A. Glucose
- B. Ketone bodies
- C. Fructose
- D. Fatty acids
Explanation: During prolonged starvation, the brain adapts to use ketone bodies made by the liver, greatly reducing its dependence on glucose.
Correct answer: Ketone bodies- A. Enzymes
- B. Vitamins
- C. Minerals
- D. None of the above
Explanation: The citric acid cycle is the final common oxidative pathway for carbohydrates, fatty acids and many amino acids, but none of these…
Correct answer: None of the above16. Which one of the following enzymes provides a link between glycolysis and the citric acid cycle ?
- A. Lactate dehydrogenase
- B. Pyruvate kinase
- C. Pyruvate dehydrogenase
- D. Citrate synthase
Explanation: The pyruvate dehydrogenase complex converts glycolytic pyruvate into acetyl-CoA, which enters the citric acid cycle.
Correct answer: Pyruvate dehydrogenase- A. Vitamin C
- B. Pyridoxine
- C. Niacin
- D. Thiamine
Explanation: Thiamine pyrophosphate is required by pyruvate dehydrogenase, so thiamine deficiency blocks conversion of pyruvate to acetyl-CoA.
Correct answer: Thiamine- A. Krebs cylce
- B. EMP pathway
- C. Urea cycle
- D. Electron transfer
Explanation: The Embden-Meyerhof pathway, or glycolysis, occurs in the cytosol. The Krebs cycle and electron-transfer chain occur in mitochondria…
Correct answer: EMP pathway- A. NADPH
- B. D fructose 6 phosphate
- C. D sedoheptulose 5 phosphate
- D. D glyceraldehyde 3 phosphate
Explanation: The HMP shunt produces NADPH and intermediates such as fructose-6-phosphate, glyceraldehyde-3-phosphate, and sedoheptulose-7-phosphate.
Correct answer: D sedoheptulose 5 phosphate- A. Enolase
- B. Phosphoglycero mutase
- C. Aldolase
- D. Glycerophosphate dehydrogenase
Explanation: Enolase, phosphoglycerate mutase and aldolase are glycolytic enzymes. Glycerophosphate dehydrogenase functions mainly in the…
Correct answer: Glycerophosphate dehydrogenaseMetabolism and Bioenergetics MCQs: common questions
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