Increase in pyruvate and lactate is seen in which of the following deficiency ?
Correct answer: D. Thiamine
- A. Vitamin C
- B. Pyridoxine
- C. Niacin
- D. Thiamine
Explanation
Thiamine pyrophosphate is required by pyruvate dehydrogenase, so thiamine deficiency blocks conversion of pyruvate to acetyl-CoA. The accumulated pyruvate is consequently diverted to lactate.
Report an error
The more specific you are, the faster it gets fixed. A source beats an opinion.
Prefer email? [email protected]
Practise Metabolism and Bioenergetics
68 free Metabolism and Bioenergetics MCQs from Biochemistry, each with the correct answer and an explanation. Unlimited attempts, no account needed.
Discussion
Stuck on an option, or know a faster way to get there? Ask or explain it here.
No comments yet. Be the first to explain this one.
Exams that ask Biochemistry questions like this
Biochemistry is on 6 papers prepared for on TestUstad, and all of them draw the same bank, so this question is worth knowing for every one of them.
More Metabolism and Bioenergetics questions
Which one of the following enzymes provides a link between glycolysis and the citric acid cycle ?
The citric acid cycle is the final pathway for oxidation of______________?
In prolonged starvation the main nergy source of brain is_____________?
All these reactions take place inside the mitochondria except____________?
Which of the following is not a product of HMP shunt_____________?
An enzyme not involved in glycolysis is______________?