Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to lack of_____________?
Correct answer: B. Homogentisate oxidase
- A. Parahydroxy phenyl pyruvate Hydroxylase
- B. Homogentisate oxidase
- C. Tyrosine transaminase
- D. Tyrosine oxidase
Explanation
Alkaptonuria results from deficiency of homogentisate oxidase in tyrosine degradation. Homogentisic acid then accumulates and may darken urine and connective tissues.
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