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Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to lack of_____________?

Correct answer: C. Homogentisate oxidase

  • A. Parahydroxy phenyl pyruvate Hydroxylase
  • B. Tyrosine transaminase
  • C. Homogentisate oxidase
  • D. Tyrosine oxidase

Explanation

Alkaptonuria results from deficiency of homogentisate oxidase in tyrosine degradation. Homogentisic acid then accumulates and may darken urine and connective tissues.

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