The severe joint pain of gout, most often felt in the big toe, is caused by the deposition of
Correct answer: D. sodium urate crystals
- A. calcium phosphate
- B. cholesterol
- C. collagen fibres
- D. sodium urate crystals
Explanation
Gout follows a raised blood level of uric acid, the end product of purine breakdown, which crystallises as sodium urate in a cool peripheral joint and provokes intense inflammation. This is why treatment lowers uric acid production or increases its excretion and why purine rich foods such as red meat and organ meat are restricted. Calcium salts harden bone rather than inflame joints.
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About Arthritis
Arthritis refers to disorders involving inflammation, damage or degeneration of joints, causing pain, stiffness and restricted movement. Coverage includes osteoarthritis caused mainly by cartilage wear and rheumatoid arthritis caused by autoimmune inflammation, which must be distinguished from osteoporosis, a disease of bone density.
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