Osteoarthritis is caused by

  • A. an autoimmune attack on the synovial membrane
  • B. deposition of uric acid crystals in the joint
  • C. gradual wear and degeneration of the articular cartilage
  • D. bacterial infection of the joint cavity

Explanation

Osteoarthritis is a mechanical, degenerative condition in which the articular cartilage thins with age and use until bone rubs on bone, so it strikes the weight bearing knee and hip of older and overweight people first. Autoimmune attack on the synovial membrane is rheumatoid arthritis, a different disease with a different cause, and uric acid deposition is gout.

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