Successful regeneration of a damaged epithelium requires preservation of the:

Correct answer: C. Underlying basement membrane and stromal framework

  • A. Local supply of adipose tissue
  • B. Entire original population of mature cells
  • C. Underlying basement membrane and stromal framework
  • D. Surrounding layer of skeletal muscle

Explanation

An intact basement membrane and stromal framework guide the migration and organization of surviving epithelial cells during regeneration. When this supporting framework is destroyed, healing is more likely to occur by fibrous scar formation.

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