Storage diseases are caused by the excessive accumulation of substances within the cell, due to defects(mutations) in one of the _ enzymes.

Explanation

Storage diseases, also known as lysosomal storage diseases, are a group of genetic disorders caused by defects (mutations) in lysosomal enzymes. Lysosomes are membrane-bound organelles responsible for cellular digestion and recycling. They contain various enzymes that break down and degrade cellular waste, toxins, and excess substances.When lysosomal enzymes are defective or deficient, the substances they normally break down accumulate within the cell, leading to cellular dysfunction and disease. Examples of lysosomal storage diseases include:- Tay-Sachs disease- Gaucher's disease- Pompe disease- Fabry disease