A patient takes tetracycline with an aluminium-containing antacid. Which effect should the nurse anticipate?
Correct answer: B. Reduced tetracycline absorption
- A. Increased tetracycline absorption
- B. Reduced tetracycline absorption
- C. Faster tetracycline metabolism
- D. Greater tetracycline protein binding
Explanation
Aluminium can bind with tetracycline in the gastrointestinal tract and form a poorly absorbed complex. This interaction reduces antibiotic absorption, so the medicines should be separated as prescribed.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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