A patient has severe metabolic acidosis, visual disturbance and altered consciousness after ingesting an unknown solvent. Methanol poisoning is suspected. Which antidote specifically blocks formation of toxic methanol metabolites?
Correct answer: A. Fomepizole
- A. Fomepizole
- B. Deferoxamine
- C. Protamine sulfate
- D. N-acetylcysteine
Explanation
Fomepizole inhibits alcohol dehydrogenase and reduces the formation of toxic methanol metabolites. Deferoxamine binds iron, protamine reverses heparin, and N-acetylcysteine treats acetaminophen toxicity.
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About Emergency Drugs and Antidotes
Emergency pharmacology covers drugs used in cardiac arrest, shock, severe allergy, acute asthma, seizures, poisoning and hypoglycaemia, including adrenaline, atropine, naloxone, flumazenil and selected antidotes. The focus is on indications, routes, rapid adverse effects, dose safety and matching a toxic substance with its specific reversal agent.
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