A patient develops sweating, abdominal cramps, diarrhoea, and muscle aches after stopping long-term opioid use. Which medication may be prescribed to reduce autonomic withdrawal symptoms?
Correct answer: A. Clonidine
- A. Clonidine
- B. Flumazenil
- C. Disulfiram
- D. Acamprosate
Explanation
Clonidine, an alpha-2 adrenergic agonist, can reduce sweating, restlessness, tachycardia, and other autonomic symptoms of opioid withdrawal. It does not replace opioid agonist treatment and may cause hypotension, so blood pressure requires monitoring.
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About Substance Use Disorders
Substance use disorders cover problematic use, intoxication, tolerance, dependence, withdrawal, and the effects of alcohol, opioids, sedatives, stimulants, cannabis, and other substances. The topic includes assessment, overdose and withdrawal management, detoxification, motivational interviewing, relapse prevention, and the difference between physical dependence and addiction.
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