A competitive antagonist at a receptor usually produces which pharmacological effect?
Correct answer: A. It shifts the agonist dose-response curve to the right
- A. It shifts the agonist dose-response curve to the right
- B. It shifts the agonist dose-response curve to the left
- C. It permanently increases the agonist maximum effect
- D. It produces the same effect as the agonist alone
Explanation
A competitive antagonist competes reversibly with an agonist at the same receptor site, so a higher agonist concentration is needed to produce the same response. Therefore, the curve shifts right without necessarily reducing the maximum response.
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Covers how drugs act in animals, including pharmacokinetics, pharmacodynamics, routes of administration, dosage forms, adverse effects and drug interactions. Major groups include antimicrobials, antiparasitics, analgesics, anaesthetics, anti-inflammatory drugs, hormones and cardiovascular medicines, with attention to withdrawal periods and species differences.
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