Free Systemic Pathology MCQs with Answers

• A. Increased liver glycogenolysis
• B. Causes broachiolar constriction
• C. Evokes extrasystoles in the heart
• D. Produces restlessness and anxiety

Explanation: High-dose intravenous epinephrine causes bronchodilation through β2-receptor stimulation, not bronchoconstriction.

• A. Penicillinase
• B. Pryosulphate
• C. Protamine sulphate
• D. Potassium sulphate

Explanation: Protamine sulphate is a strongly basic protein that binds acidic heparin and neutralises its anticoagulant effect.

• A. Testosterone
• B. Parathyroid
• C. Insulin
• D. Thyroid

Explanation: Excess thyroid hormone increases tissue responsiveness to catecholamines, partly by increasing β-adrenergic receptor effects.

• A. Lowers the intraocular pressure in glaucoma
• B. Cleaved by acetylcholinesterase
• C. Inhibits sweat and lacrimation
• D. Causes tachycardia

Explanation: Pilocarpine is a direct muscarinic agonist that contracts the ciliary muscle and increases aqueous outflow, thereby lowering intraocular…

• A. Atropine
• B. Diazepam
• C. Succinylcholine
• D. Neostigmine

Explanation: Succinylcholine rapidly produces skeletal-muscle paralysis and is used to relax the laryngeal muscles during severe laryngospasm.

• A. Corticosteroids
• B. Antihistamines
• C. Diazepam
• D. Adrenalin

Explanation: Adrenaline is the first-line treatment for life-threatening anaphylaxis because it rapidly reverses bronchoconstriction, vasodilation and…

• A. Antacids
• B. Benzodiazepine
• C. Codeine, dihydrocodeine, paracetmol
• D. Nsaid's like Ibuprofen

Explanation: Ibuprofen and other NSAIDs increase bleeding risk with warfarin by impairing platelet function and damaging the gastric mucosa, in…

• A. Bronchial muscle relaxationConsult Online Doctors
• B. Contraction of urinary spinctors
• C. Vasoconstriction
• D. Mydriasis

Explanation: Beta2 stimulation relaxes bronchial smooth muscle, producing bronchodilation.

• A. choline, adrenaline and amphetamine
• B. Pancuronium, rocuronium
• C. Glycinium neostigamine and physostigamine
• D. Pirenzipine, propanolol and propantheline

Explanation: Pancuronium and rocuronium are non-depolarizing neuromuscular blockers that competitively inhibit nicotinic receptors at the neuromuscular…

• A. D-tubocurarine
• B. Gallamine triethiodide
• C. Succinylcholine
• D. Pancuronium bromide

Explanation: D-tubocurarine, gallamine and pancuronium are non-depolarizing blockers, whereas succinylcholine first depolarizes the motor end plate and…

• A. Bradycardia
• B. Decreased Salivation
• C. Decreased Sweating
• D. Mydriasis

Explanation: Atropine blocks muscarinic vagal effects, causing dry mouth, reduced sweating and mydriasis; at usual doses it tends to produce…

• A. Fontania stain
• B. PAS
• C. Ferrous trichrome
• D. Pearls prussian blue

Explanation: Periodic acid-Schiff stain highlights fungal cell-wall carbohydrates, making fungi readily visible in tissue sections.

• A. Osteogenic sarcoma
• B. Ewings sarcoma
• C. Osteoclastoma
• D. Chondro sarcoma

Explanation: A tumour centred in the epiphysis of a long bone is classically a giant cell tumour, also called osteoclastoma.

• A. Ewing's sarcoma
• B. Giant cell tumourOrder DNA Kits
• C. Chondrosarcoma
• D. Osteosarcoma

Explanation: In an adolescent, a mixed lytic and blastic lesion in the metaphysis near the knee strongly indicates osteosarcoma.

• A. Viral meningitis
• B. Pyogenic bacterial meningitis
• C. Fungal meningitis
• D. Tuberculous meningitis

Explanation: A lymphocyte-predominant CSF with normal glucose and normal or mildly raised protein is typical of viral meningitis.

• A. 2
• B. 4
• C. 6
• D. 9

Explanation: Cartilage commonly contains type II collagen with smaller amounts of types VI, IX and XI, whereas type IV is characteristic of basement…

• A. Medulla oblongata
• B. Spinal card
• C. Basal cisternae
• D. Brain parenchyma

Explanation: The brain parenchyma is the commonest site of intracranial neurocysticercosis, where cysts may be seen in different stages of…

• A. lepromatous leprosy
• B. Ideterminate leprosy
• C. Borderline tuberculoid leprosy
• D. Tuberculoid leprosy

Explanation: Virchow cells are lipid-laden macrophages packed with Mycobacterium leprae and are characteristic of lepromatous leprosy.

• A. Gonorrhea
• B. Tuberculosis
• C. AIDS
• D. Syphilis

Explanation: A Ghon focus is the small primary parenchymal lesion of pulmonary tuberculosis, usually accompanied by involved hilar lymph nodes to form…

• A. Undergoes cavitation
• B. Progresses to tuberculous pneumonia
• C. Undergoes calcification
• D. Progresses to military tuberculosis

Explanation: A primary tuberculous Ghon complex commonly heals by fibrosis and calcification, sometimes becoming a Ranke complex.