Free Inflammation and Repair MCQs with Answers

53 Inflammation and Repair MCQs from Pathology, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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  • A. Elie Metchnikoff
  • B. Celsus
  • C. Virchow
  • D. None of the above

Explanation: Elie Metchnikoff discovered phagocytosis while studying the uptake of particles by mobile cells in starfish larvae.

Correct answer: Elie Metchnikoff
  • A. Lymphocytes
  • B. Vacuolated Histocytes
  • C. Plasma cells
  • D. NeutrophilsConsult Online Doctors

Explanation: Lepra cells are foamy macrophages packed with Mycobacterium leprae and lipid, giving them a vacuolated appearance.

Correct answer: Vacuolated Histocytes
  • A. Monocytes
  • B. Lymphocytes
  • C. PMN's
  • D. Eosinophils

Explanation: Suppuration is mainly produced by neutrophils, whose lysosomal enzymes digest tissue and form pus.

Correct answer: PMN's
  • A. Transudation -> exudation -> oedena
  • B. Oedema -> exudation
  • C. Exudation -> transudation -> oedema
  • D. Only by exudation -> oedema

Explanation: In acute inflammation, increased hydrostatic pressure may first produce a protein-poor transudate; increased vascular permeability then…

Correct answer: Transudation -> exudation -> oedena
  • A. All of the above
  • B. Leprosy
  • C. Tuberculosis
  • D. Sarcoidosis

Explanation: Sarcoidosis, leprosy, and tuberculosis all produce granulomatous inflammation, characterized by collections of activated macrophages…

Correct answer: All of the above
  • A. T cells
  • B. B cells
  • C. MonocyteConsult Online Doctors
  • D. Plasma cells

Explanation: Epithelioid cells and multinucleated giant cells in a granuloma arise from activated macrophages, which are derived from monocytes.

Correct answer: MonocyteConsult Online Doctors
  • A. Arachidonic acid is metabolized to form prostaglandins and leukotrienes
  • B. Leukotrienes cause bronchoconstriction
  • C. COX is induced by cytokines at the site of inflammation
  • D. COX-1 is inducible in many tissues

Explanation: COX-1 is generally constitutive and maintains normal gastric, renal and platelet functions, whereas inducible COX-2 is increased by…

Correct answer: COX-1 is inducible in many tissues
  • A. Tuberculosis
  • B. Viral infections
  • C. Tyhoid
  • D. AmoebiasisTrack Health Symptoms

Explanation: Caseation is a cheese-like form of necrosis classically produced by Mycobacterium tuberculosis within tuberculous granulomas.

Correct answer: Tuberculosis
  • A. Tuberculoid leprosy
  • B. Lepromatous leprosy
  • C. Histoid leprosy
  • D. Intermediate leprosy

Explanation: Lepra cells are foamy macrophages packed with Mycobacterium leprae and are abundant in lepromatous leprosy, where cell-mediated immunity…

Correct answer: Lepromatous leprosy
  • A. Exudative
  • B. Granulomatous
  • C. Necrotizing
  • D. Cytopathic

Explanation: Granulomatous inflammation is a pattern of chronic inflammation involving persistent macrophage activation, not a typical acute…

Correct answer: Granulomatous
  • A. RNA template
  • B. Rough endoplasmic reticulum
  • C. Polyunsaturated fatty acids
  • D. None of the above

Explanation: Prostaglandins are lipid mediators formed from membrane polyunsaturated fatty acids, especially arachidonic acid, through the…

Correct answer: Polyunsaturated fatty acids
  • A. A specific type of chronic inflammation
  • B. Accumulation of modified macrophages
  • C. Initiated by a number of infectious and non infectious agents
  • D. A reaction of acute inflammationTrack Health Symptoms

Explanation: A granuloma is a specialised form of chronic inflammation consisting mainly of aggregated epithelioid macrophages, often with giant cells…

Correct answer: A reaction of acute inflammationTrack Health Symptoms
  • A. Sulfatide
  • B. Surface glycolipids
  • C. Hetero polysaccharide
  • D. Sulfadase

Explanation: Surface glycolipids of Mycobacterium tuberculosis contribute to macrophage activation and the granulomatous response.

Correct answer: Surface glycolipids
  • A. Coagulase
  • B. Peroxidase
  • C. Hyaluronidase
  • D. Bradykinin

Explanation: Hyaluronidase breaks down hyaluronic acid in connective tissue, allowing organisms and inflammatory fluid to spread through tissue, so it…

Correct answer: Hyaluronidase
  • A. Tuberculosis
  • B. SarcoidosisTry Prep Courses
  • C. Syphilis
  • D. Granulation tissue

Explanation: Epithelioid cells are activated macrophages typical of granulomas in tuberculosis, syphilis and sarcoidosis.

Correct answer: Granulation tissue
  • A. Formation of blood cloth
  • B. Organization
  • C. Epithelial changes
  • D. Acute inflammatory response

Explanation: The earliest event in healing of a clean wound is formation of a blood clot, which seals the defect and provides a provisional matrix.

Correct answer: Formation of blood cloth
  • A. Nutrition
  • B. All of the aboveConsult Injury Lawyers
  • C. Size and location of wound
  • D. Adequate blood supply

Explanation: Healing requires adequate nutrition, especially protein, good blood supply and oxygen, and is also affected by the wound's size and…

Correct answer: All of the aboveConsult Injury Lawyers
  • A. Fibroblast
  • B. Macrophages
  • C. Polymorphs
  • D. Budding blood vessels

Explanation: The essential components of granulation tissue are proliferating fibroblasts, newly formed capillaries and inflammatory cells such as…

Correct answer: Polymorphs
  • A. Steroids
  • B. Protein
  • C. Vitamin C
  • D. Adequate oxygen supply

Explanation: Protein, vitamin C and adequate oxygen support collagen synthesis and tissue repair.

Correct answer: Steroids
  • A. Distal end
  • B. Proximal end
  • C. Both A and B
  • D. None of the above

Explanation: After nerve transection, axonal sprouts arise from the viable proximal stump and may grow toward the distal segment.

Correct answer: Proximal end