Free Immunisation and EPI MCQs with Answers

50 Immunisation and EPI MCQs from Paediatric Nursing, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

Immunisation covers active and passive immunity, vaccine types, routine childhood schedules under Pakistan’s Expanded Programme on Immunization, administration routes and age-based timing. It also includes cold-chain maintenance, contraindications, adverse events following immunisation, missed doses and the distinction between vaccine protection and treatment of an established infection.

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50 questions · page 3 of 3

  • A. It develops memory cells after vaccination
  • B. It gives immediate protection without lasting immune memory
  • C. It requires exposure to a weakened microorganism
  • D. It usually provides lifelong protection after one dose

Explanation: Passive immunity comes from ready-made antibodies and acts quickly, but it does not usually create immune memory.

Correct answer: It gives immediate protection without lasting immune memory
  • A. Live attenuated vaccine
  • B. Inactivated whole-cell vaccine
  • C. Subunit vaccine
  • D. Toxoid vaccine

Explanation: A subunit vaccine contains purified components, such as proteins or polysaccharides, that stimulate immunity.

Correct answer: Subunit vaccine
  • A. In the refrigerator door shelves
  • B. Against the freezer compartment wall
  • C. On the middle shelves away from the door
  • D. Beside the refrigerator light bulb

Explanation: Vaccines should be kept on the middle shelves where the temperature is more stable.

Correct answer: On the middle shelves away from the door
Moderate
  • A. Leave them there because the door is easy to access
  • B. Move them to the recommended shelves and check their condition
  • C. Place them beside the freezer to cool them quickly
  • D. Discard every vaccine immediately without assessment

Explanation: The nurse should move vaccines to the correct shelves and assess temperature records, expiry dates and VVM status.

Correct answer: Move them to the recommended shelves and check their condition
Hard
  • A. Send the child home after the seizure stops
  • B. Record and promptly report the serious AEFI through the EPI system
  • C. Give the same vaccine again to confirm the reaction
  • D. Wait for the next routine immunisation session to report it

Explanation: A serious AEFI requires accurate documentation and prompt notification through the designated EPI reporting system after the child is…

Correct answer: Record and promptly report the serious AEFI through the EPI system
  • A. Recap it with two hands before disposal
  • B. Bend it before placing it in the waste bin
  • C. Place it immediately in a puncture-resistant safety box
  • D. Leave it on the tray until the session has ended

Explanation: Used needles should be placed immediately into a puncture-resistant safety box without recapping, bending or handling them again.

Correct answer: Place it immediately in a puncture-resistant safety box
Moderate
  • A. Touch the dropper tip to the child’s lips
  • B. Place the dropper tip inside the child’s mouth
  • C. Keep the dropper tip away from the mouth and tongue
  • D. Mix the vaccine with leftover milk in a feeding bottle

Explanation: The dropper tip should not touch the child’s mouth because this can contaminate the vial.

Correct answer: Keep the dropper tip away from the mouth and tongue
  • A. They contain a live bacterium that multiplies in the intestine
  • B. They link a polysaccharide antigen to a protein carrier to improve the immune response
  • C. They contain antibodies collected from an immune donor
  • D. They destroy bacteria already multiplying in the child’s blood

Explanation: Conjugate vaccines link a polysaccharide antigen to a protein carrier, producing a stronger and more reliable response in young children.

Correct answer: They link a polysaccharide antigen to a protein carrier to improve the immune response
Moderate
  • A. This always means the child has a severe allergy
  • B. These mild reactions can occur and usually settle with observation and comfort care
  • C. The child must never receive another vaccine
  • D. The child needs antibiotics immediately for vaccine infection

Explanation: Mild soreness, swelling or low-grade fever can occur after immunisation and usually resolves without antibiotics.

Correct answer: These mild reactions can occur and usually settle with observation and comfort care
  • A. Vaccination only benefits children who have already been infected
  • B. Vaccination helps protect the child and reduces spread within the community
  • C. Vaccination replaces handwashing and safe drinking water
  • D. Vaccination treats infections after symptoms have started

Explanation: Vaccination directly protects the child and also reduces transmission, helping protect people who cannot be fully vaccinated.

Correct answer: Vaccination helps protect the child and reduces spread within the community