Free Molecular Biology MCQs with Answers

38 Molecular Biology MCQs from Biochemistry, each with the correct answer and a written explanation of why it is correct. Free and unlimited, with no account needed.

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  • A. DNA polymerase
  • B. Reverse transcriptase
  • C. RNA polymerase
  • D. Phospho kinase

Explanation: Reverse transcriptase synthesises DNA using an RNA template, producing a complementary DNA strand and ultimately a double-stranded DNA…

Correct answer: Reverse transcriptase
  • A. Protein storage
  • B. m RNA synthesis
  • C. Modification of proteins
  • D. t RNA synthesis

Explanation: The Golgi apparatus modifies, sorts, and packages proteins received from the endoplasmic reticulum, including glycosylation and…

Correct answer: Modification of proteins
  • A. Mitochondria
  • B. Golgi bodies
  • C. Nucleus
  • D. Poly ribosomes

Explanation: Protein synthesis occurs on ribosomes, and multiple ribosomes translating the same mRNA form a polyribosome or polysome.

Correct answer: Poly ribosomes
  • A. Mitochondria
  • B. Endoplasmic reticulum
  • C. Nucleolus
  • D. Plasma membrane

Explanation: Most cytoplasmic ribosomes are attached to the rough endoplasmic reticulum, where they synthesise proteins destined for secretion…

Correct answer: Endoplasmic reticulum
  • A. Protein lipid synthesis
  • B. Protein synthesis
  • C. Sorting of glycoproteins
  • D. None of the above

Explanation: The Golgi apparatus modifies, sorts, and packages glycoproteins for delivery to their correct destinations.

Correct answer: Sorting of glycoproteins
  • A. Centriole
  • B. Golgi body
  • C. Endoplasmic reticulum
  • D. Mitochondrion

Explanation: Mitochondria contain their own circular DNA and replicate semi-autonomously.

Correct answer: Mitochondrion
  • A. Lysomes
  • B. Rough endoplasmic reticulum
  • C. Golgi apparatus
  • D. Mitochondria

Explanation: Lysosomes function as the cell’s digestive compartments because their acid hydrolases degrade proteins, lipids, nucleic acids, and…

Correct answer: Lysomes
  • A. c AMP
  • B. c GMP
  • C. Phosphatidyl glycerol
  • D. Phosphatidyl inosital

Explanation: Phosphatidylglycerol is a membrane phospholipid and is not a standard second messenger.

Correct answer: Phosphatidyl glycerol
  • A. Ribsomes
  • B. Nucleolus
  • C. Golgi apparatus
  • D. Nucleus

Explanation: The nucleus contains the cell's nuclear DNA and is therefore the expected answer among these options.

Correct answer: Nucleus
  • A. G Proteins act as inhibitory and excitatory because of difference in alpha subunit
  • B. All the three subunits alpha, beta and gamma should bind each other for G protein to act
  • C. G proteins bind to hormones on the cell surface
  • D. G protein is bound to GTP in resting stateOrder DNA Kits

Explanation: G-protein effects can be stimulatory or inhibitory largely because different alpha subunits activate or inhibit target enzymes such as…

Correct answer: G Proteins act as inhibitory and excitatory because of difference in alpha subunit
  • A. Integrin a6-B4
  • B. The catenins desmoplakin
  • C. cadherins desmoglein
  • D. a and B catenin

Explanation: Hemidesmosomes use integrin α6β4 to attach epithelial cells to laminin in the basal lamina.

Correct answer: Integrin a6-B4
  • A. Watson and Crick
  • B. Edwarg Angle
  • C. Singer and Nicolson
  • D. G.V Black

Explanation: Singer and Nicolson proposed the fluid mosaic model in 1972, describing proteins floating within a dynamic phospholipid bilayer.

Correct answer: Singer and Nicolson
  • A. Immunofluoresence
  • B. Widal test
  • C. Electrophoresis
  • D. Real time PCR

Explanation: Real-time PCR quantitatively amplifies and detects viral nucleic acid, allowing estimation of viral load.

Correct answer: Real time PCR
  • A. Cyclic AMP
  • B. Cyclic GMP
  • C. Adenosine cyclate
  • D. Calcium release

Explanation: FSH, LH and TSH bind G-protein-coupled receptors that activate adenylate cyclase, increasing cyclic AMP as the second messenger.

Correct answer: Cyclic AMP
  • A. Post transcriptional modification
  • B. Post translation modification
  • C. DNA replication
  • D. Splicing

Explanation: RNA directly participates in post-transcriptional processing, splicing, and DNA replication through RNA primers.

Correct answer: Post translation modification
  • A. Mitochondria
  • B. Centrosome
  • C. Nucleus
  • D. Ribosome

Explanation: Translation is the ribosome-mediated reading of mRNA to assemble an amino-acid chain.

Correct answer: Ribosome
  • A. m-RNA
  • B. DNA
  • C. t-RNA
  • D. Ribosomal RNA

Explanation: Codons are three-base sequences on mRNA that specify amino acids or stop signals during translation.

Correct answer: m-RNA
  • A. Terminator
  • B. Promoter region
  • C. Operator
  • D. Anti terminator

Explanation: The promoter is the DNA region recognized by RNA polymerase to begin transcription.

Correct answer: Promoter region
  • A. Degenerate
  • B. Universal
  • C. Punctuation
  • D. Non overlapping

Explanation: The genetic code is degenerate, largely universal and non-overlapping, but it is comma-less, meaning there are no punctuation marks…

Correct answer: Punctuation
  • A. Nucleolus
  • B. Nucleus
  • C. Ribosome
  • D. Endoplasmic reticulum

Explanation: Most ribosomal RNA is transcribed and processed in the nucleolus, where ribosomal subunits begin to assemble.

Correct answer: Nucleolus

Molecular Biology MCQs: common questions

Are these Molecular Biology MCQs free?

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There are 38 Molecular Biology MCQs in the Biochemistry bank, shown 20 to a page with the correct answer and an explanation on each.

Does every Molecular Biology MCQ have an explanation?

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