Moderate

True about G protein couple receptors is _________________ ?

Correct answer: C. G Proteins act as inhibitory and excitatory because of difference in alpha subunit

  • A. G proteins bind to hormones on the cell surface
  • B. All the three subunits alpha, beta and gamma should bind each other for G protein to act
  • C. G Proteins act as inhibitory and excitatory because of difference in alpha subunit
  • D. G protein is bound to GTP in resting stateOrder DNA Kits

Explanation

G-protein effects can be stimulatory or inhibitory largely because different alpha subunits activate or inhibit target enzymes such as adenylyl cyclase. In the resting state the alpha subunit binds GDP, and hormones bind receptors rather than the G protein itself.

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