Zero order kinetics is seen with_______________?
Correct answer: A. Phenytoin
- A. Phenytoin
- B. Phenabarbtion
- C. Erythromycin
- D. Digoxin
Explanation
Phenytoin shows capacity-limited metabolism, so its elimination changes from first-order to approximately zero-order as metabolic enzymes become saturated. Ethanol and high-dose salicylates are other classic examples.
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