Zero order kinetics is seen with_______________?

Correct answer: A. Phenytoin

  • A. Phenytoin
  • B. Phenabarbtion
  • C. Erythromycin
  • D. Digoxin

Explanation

Phenytoin shows capacity-limited metabolism, so its elimination changes from first-order to approximately zero-order as metabolic enzymes become saturated. Ethanol and high-dose salicylates are other classic examples.

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