Hepatic first pass metabolism is important in____________?
Correct answer: B. Drugs taken orally
- A. Drugs given IM
- B. Drugs taken orally
- C. Drugs given IV
- D. None of the above
Explanation
Orally administered drugs are absorbed from the gastrointestinal tract and pass through the portal circulation to the liver before reaching systemic circulation, allowing first-pass metabolism. IM and IV drugs largely bypass this hepatic first-pass effect.
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