The phase I reactions of drug metabolism include The following except_____________?

Correct answer: D. Conjugation

  • A. Hydolysis
  • B. Reduction
  • C. Oxidation
  • D. Conjugation

Explanation

Phase I reactions expose or introduce functional groups through oxidation, reduction or hydrolysis. Conjugation is a Phase II reaction, which usually makes the drug more water-soluble for excretion.

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