Which statement best describes the action of cinacalcet?
Correct answer: A. It increases calcium-sensing receptor sensitivity and lowers parathyroid hormone release
- A. It increases calcium-sensing receptor sensitivity and lowers parathyroid hormone release
- B. It directly replaces calcitonin and rapidly deposits calcium into bone
- C. It blocks thyroid hormone production and reduces basal metabolism
- D. It increases intestinal calcium absorption by activating vitamin D receptors
Explanation
Cinacalcet is a calcimimetic that increases the sensitivity of calcium-sensing receptors, reducing parathyroid hormone secretion and usually lowering serum calcium. It is not a thyroid drug, vitamin D replacement or direct calcitonin preparation.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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