Moderate

A patient receiving desmopressin for central diabetes insipidus asks about daily fluid intake. Which statement shows correct understanding?

Correct answer: A. I will follow the prescribed fluid limit and report headache or confusion

  • A. I will follow the prescribed fluid limit and report headache or confusion
  • B. I will drink unlimited water to prevent every possible complication
  • C. I will stop desmopressin whenever my urine becomes less frequent
  • D. I will take extra doses if I develop mild ankle swelling

Explanation

Desmopressin reduces urine production, so excessive fluid intake can cause water retention and hyponatraemia. Headache, confusion, nausea or seizures may indicate serious hyponatraemia and require urgent reporting.

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About Endocrine and Diabetes Drugs

Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.

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