A patient takes levothyroxine each morning and has recently started taking calcium carbonate. Which teaching is correct?
Correct answer: A. Take calcium at least four hours apart from levothyroxine
- A. Take calcium at least four hours apart from levothyroxine
- B. Take both medicines together after the evening meal
- C. Stop levothyroxine whenever calcium is prescribed
- D. Crush both medicines and mix them in fruit juice
Explanation
Calcium can bind levothyroxine in the gastrointestinal tract and reduce its absorption, so the medicines should be separated by at least four hours. Levothyroxine should not be stopped without prescriber direction.
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About Endocrine and Diabetes Drugs
Endocrine pharmacology includes insulin preparations, oral antidiabetic drugs, thyroid and antithyroid medicines, corticosteroids, sex hormones and drugs affecting calcium balance. Questions address onset and duration, administration, monitoring, hypoglycaemia, steroid adverse effects and the difference between replacing a deficient hormone and suppressing excessive hormone activity.
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