Which one of the following does NOT act by increasing insulin secretion______________?
Correct answer: D. Biguanide
- A. Glyburide
- B. Repaglinide
- C. Tolbutamide
- D. Biguanide
Explanation
Biguanides such as metformin lower glucose mainly by reducing hepatic gluconeogenesis and improving insulin sensitivity, without stimulating insulin release. Glyburide, repaglinide and tolbutamide are insulin secretagogues.
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