Asked in UHS MDCAT 2016 2016Moderate

Which of the following is an example of autosomal non-disjunction?

Correct answer: D. Down's syndrome

  • A. Turner's Syndrome
  • B. Jacob's Syndrome
  • C. Metastasis
  • D. Down's syndrome

Explanation

Non-disjunction causes an abnormal number of chromosomes in all cells, called aneuploidy, or in some cells, called mosaicism. Some of the important examples are Down's syndrome and trisomy of autosomes, i.e., chromosome 21. It contains one extra chromosome 21.

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Chromosomes are DNA-protein structures that carry genes and become visible during cell division. Coverage includes chromatin, centromeres, sister chromatids, homologous chromosomes, chromosome number, and the distinction between diploid and haploid cells, with links to DNA replication, mitosis and meiosis.

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